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Name Mr. Teng Yuan
Organization or Institution University of South Florida
Presentation Type Poster
Topic Organic Chemistry
Title

Triazole-Imidazole (TAIM) as Novel Fluorescence Probe for Selective Ag+ Cation Detection with PPM Scale

Author(s)

Qi Lai, Teng Yuan, Xiaodong Shi

Author Institution(s)

University of South Florida

Abstract

A gold catalyzed oxidative alkyne coupling was developed as an efficient approach for the synthesis of challenging cyclic conjugated diyne.  Compared to copper promoted oxidative alkyne coupling, gold complexes gave much faster reaction due to a faster reductive elimination from Au(III) intermediates.  This unique reactivity allowed macrocyclization under dilute conditions with good overall reactivity.  Condition screening revealed crucial combination of [(n-Bu)4N]+[Cl-Au-Cl]-  as the catalyst and Phen-ligand for successful relativities.   Ring structures with size between 14 to 20 atoms were prepared in good to excellent yields while copper catalysts gave poor results, which highlighted the unique advantage of this new strategy.